Advanced Search   

Customer Service info@echemshop.com +1-302-292-8500

10754 Methoxytrityl-N-dPEG 16-TFP ester

Quick Overview

CAS: 1334169-92-4

Item Name: Methoxytrityl-N-dPEG 16-TFP ester

Item #: 10754

Mol. Wt.: 1232.32;

single compound dPEG Spacer is 52 atoms and 61.5 A

10754 Methoxytrityl-N-dPEG 16-TFP ester

* Required Fields

Details

CAS: 1334169-92-4
Item Name: Methoxytrityl-N-dPEG 16-TFP ester
Item #: 10754
Mol. Wt.: 1232.32;
single compound dPEG Spacer is 52 atoms and 61.5 A
Product Features and Benefits: Useful for incorporating the a protected amine whose protecting group is orthogonal to the Fmoc or t-boc protecting groups. AND is contains the very powerfully useful dPEG containing pegylation spacer chain. In this case it contains 4 dPEG units. The dPEG pegylation spacer has all the powerful properties of the dPEG , including its high water solubility, non-immunogenicity, and non- aggregating properties Mmt can be removed under a number of conditions, but we find that using 20% TFE (trifluoroethanal) in methylene choride is most effective.
References: Some references to the use of the Mmt as an amino protection groups with amino acids: a) G.M. Dubowchik and S. Rakia, Tetrahedron Letters, 38(30), 5257-5260 (1997); b) S. Matysiak, et al., ibid., 39, 1733-1734 (1998); c) D. W. Will, et al., Tetrahedron, 51 (44), 12069-12082 (1995); d) A. Aletras, et al., Int. J. Peptide Prtein Res., 45,488-496 (1995)