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eChemShop - Chemical Reagents, Natural Compounds, Software, HPLC columns :: Natural Products :: ST065835 Gossypol

ST065835 Gossypol

Gossypol (Gossipol)

Polyphenol C30H30O8 from plants of the Gossypium genus, Malvaceae. Lipophilic agent derived from cottonseed. Exhibits multiple biological effects including antifertility and anticancer activity. Gossypol is available for large-scale (1, 10, 100 kg) production at our facilities. Please send us a message or call with bulk inquiries.

Chemical name: 1,1',6,6',7,7'-Hexahydroxy-3,3'- dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]- 8,8'-dicarboxaldehyde

Molecular Weight: 518.56
Melting Point: 177-182°C (decomp.)
Purity min.: 98%
CAS Number: 303-45-7
Store at -20°C
Soluble to 25 mM in ethanol and to 25 mM in DMSO

About Gossypol, Definitions of Gossypol

- An anticancer drug extracted from the cotton plant

- Gossypol is a polyphenol C30H30O8derived from the cottonseed plant (genus Gossypium, family Malvaceae)used as a male oral contraceptive in China. Its efficacy is comparable to the female birth control pill.

- A pigment normally found in cotton which gives this crop some resistance to insects

Additional information about Gossypol:

A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.

GOSSYPIUM

A plant genus of the family MALVACEAE. It is the source of COTTON FIBER; COTTONSEED OIL, which is used for cooking, and GOSSYPOL. The economically important cotton crop is a major user of agricultural PESTICIDES.

References:

- Vander Jagt et al (2000) Gosspyol: prototype of inhibitors targeted to dinucleotide folds. Curr.Med.Chem. 7 479.
- Coutinho (2002) Gossypol: a contraceptive for men. Contraception 65 259.
- Zhang et al (2003) Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells. Biochem.Pharmacol. 66 93.

Attention: All products on eChemShop are for research only. Not for human use!

Details


SKU	ST065835-50
Weight	0.00 lbs
CAS#	303-45-7
Brutto-Formula	freezor -20°C, darkness
Price:	$45.00 (€ 35.41)

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