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ST023755 Salsolidine

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Salsolidine

5784-74-7

MFCD00694774

6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline

ST023755 Salsolidine

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$32.00

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IDENTIFIER
IDNUMBERNAMECASMDL
ST023755Salsolidine5784-74-7MFCD00694774
IUPACNAME
6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
Smiles
c12cc(c(cc1CCNC2C)OC)OC
TRADEMARK
INCHI
InChI=1S/C12H17NO2/c1-8-10-7-12(15-3)11(14-2)6-9(10)4-5-13-8/h6-8,13H,4-5H2,1-3H3
INCHIKEY
InChIKey=HMYJLVDKPJHJCF-UHFFFAOYSA-N
Chem-Physical
FormulaMolecular WeightSALTAbsorption
C12H17NO2207.271
LogPLogSLipinskyAcceptors
2.03-3.4642
DonorsRotation BondsChiral CentersN+O
1213
ACTIVITY
THERAPEUTIC CATEGORYVET THERAPEUTIC CATEGORY
Competitive inhibitor of catechol-O-methyltransferase Stereoselective competitive inhibitor of the enzyme monoamine oxidase
REFERENCE
Benkrief R, et al. Alkaloids and flavonoid from aerial parts of Hammada articulata ssp. scoparia. Ann Pharm Fr. 1990;48(4):219-24 Sanft K, Thomas H. Competitive inhibition of catechol-O-methyltransferase by the tetrahydroisoquinoline alkaloids salsolidine and 1-carboxysalsoline. Z Naturforsch [C]. 1989 Jan-Feb;44(1-2):173-6 Dostert P, et al. Dopamine-derived alkaloids in alcoholism and in Parkinson's and Huntington's diseases. J Neural Transm. 1988;74(2):61-74

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