10355 Biotinoylsarcosine

Amount: 1000mg

Item Name: Biotinoylsarcosine

Item #: 10355

Mol. Wt.: 315.39;

single compound

Product Features and Benefits: Building block for BIOTINIDASE RESISTANT biotinylation reagents Inquire about the NHS ester The sarcosine is one spacer that has been developed by Dr. Scott Wilbur at the University of Washington to give derived biotinylation reagents a high level of biotinidase resistance, while maintaining a high binding rate and affinity for the avidin and streptavidin

References: D. Scott Wilbur, et al., “Biotin Reagents for Antibody Pretargeting. 7. Investigation of Chemically Inert Biotinidase Blocking Functionalities for Synthetic Utility,” Bioconjugate Chemistry, 17(6), 1514-1522 (2006), and references therein. Plus Scott’s earlier papers in this area: a) ibid., 12, 616-623 (2001) and b) ibid., 8, 572-584 (1997).