10356 Biotinoyl-2-Aminobutyric acid

Amount: 1000mg

Item Name: Biotinoyl-2-Aminobutyric acid

Item #: 10356

Mol. Wt.: 329.42;

single compound

Product Features and Benefits: Building block for BIOTINIDASE RESISTANT biotinylation reagents Inquire about the NHS ester The 2-aminobutyric acid is another yet simple and effective spacer that has been developed by Dr. Scott Wilbur at the University of Washington to give derived biotinylation reagents a high level of biotinidase resistance, while maintaining a high binding rate and affinity for the avidin and streptavidin

Reference: D. Scott Wilbur, et al., “Biotin Reagents for Antibody Pretargeting. 7. Investigation of Chemically Inert Biotinidase Blocking Functionalities for Synthetic Utility,” Bioconjugate Chemistry, 17(6), 1514-1522 (2006), and references therein. Plus Scott’s earlier papers in this area: a) Bioconjugate Chemistry, 12, 616-623 (2001) and b) Bioconjugate Chemistry, 8, 572-584 (1997).