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Product Image Model- Price Item Name
(+ -) Baclofen ST075584 ST075584 $61.00

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(+ -) Baclofen ST075584

1334-47-0

MFCD00055143

C10H12ClNO2

213.66


IDENTIFIER
IDNUMBERNAMECASMDL
ST075584(+ -) Baclofen1134-47-0MFCD00055143
IUPACNAME
4-amino-3-(4-chlorophenyl)butanoic acid
Smiles
C(CC(c1ccc(Cl)cc1)CN)(=O)O
Trademark
Lioresal
Chem-Physical
FormulaMolecular WeightSALT
C10H12ClNO2213.66
LogPLogSLipinskyAcceptors
1.78-3.1942
DonorsRotation BondsChiral CentersN+O
3413
ACTIVITY
THERAPEUTIC CATEGORYVET THERAPEUTIC CATEGORY
Muscle Relaxant, Antispastic
Muscle Relaxant, Antispastic Agent
selective GABA B receptor antagonist
inhibits excitatory transmission by interacting with a bicuculline-insensitive gamma-aminobutyric acid receptor
REFERENCE
Polc P, Haefely W. Effects of two benzodiazepines, phenobarbitone, and baclofen on synaptic transmission in the cat cuneate nucleus. Naunyn Schmiedebergs Arch Pharmacol. 1976 Aug;294(2):121-31
Ault B, Nadler JV. Baclofen selectively inhibits transmission at synapses made by axons of CA3 pyramidal cells in the hippocampal slice. J Pharmacol Exp Ther. 1982 Nov;223(2):291-7

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(-)Galanthamine ST056188 ST056188 $61.00

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(-)Galanthamine ST056188

19453

MFCD00601334

C17H21NO3

287.36


IDENTIFIER
IDNUMBERNAMECASMDL
ST056188(-)Galanthamine357-70-0MFCD00601334
IUPACNAME
(1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0<1,12>.0<6,17>]h eptadeca-6,8,10(17),15-tetraen-14-ol
Smiles
c1cc(c2c3c1CN(CC[C@]13C(O2)C[C@H](C=C1)O)C)OC
Chem-Physical
FormulaMolecular WeightSALT
C17H21NO3287.36
LogPLogSLipinskyAcceptors
2.78-4.0943
DonorsRotation BondsChiral CentersN+O
1134
SOURCE
Galanthus Krasnovii A. Chochr.
REFERENCE
Auchus AP, et al. Galantamine treatment of vascular dementia: a randomized trial. Neurology. 2007 Jul 31;69(5):448-58
Coyle JT, et al. Beyond in vitro data: a review of in vivo evidence regarding the allosteric potentiating effect of galantamine on nicotinic acetylcholine receptors in Alzheimer's neuropathology. J Alzheimers Dis. 2007 Aug;11(4):491-507
Daiello LA. Atypical antipsychotics for the treatment of dementia-related behaviors: an update. Med Health R I. 2007 Jun;90(6):191-4
Hansen SB, Taylor P. Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors. J Mol Biol. 2007 Jun 15;369(4):895-901. Epub 2007 Mar 31
Asoeva EZ, et al. Galanthus Krasnovii A. Chochr.--a source for obtaining galanthamine. Farmatsiia. 1968 Sep-Oct;17(5):47-9

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1-(2-Trifluoromethylphenyl)imidazole, TRIM ST075546 ST075546 $61.00

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1-(2-Trifluoromethylphenyl)imidazole, TRIM ST075546

25371-96-4

MFCD00041206

C10H7F3N2

212.17


IDENTIFIER
IDNUMBERNAMECASMDL
ST0755461-(2-Trifluoromethylphenyl)imidazole, TRIM25371-96-4MFCD00041206
IUPACNAME
[2-(trifluoromethyl)phenyl]imidazole
Smiles
c1(n2cncc2)ccccc1C(F)(F)F
Trademark
Chem-Physical
FormulaMolecular WeightSALT
C10H7F3N2212.17
LogPLogSLipinskyAcceptors
2.72-3.640
DonorsRotation BondsChiral CentersN+O
0002
ACTIVITY
THERAPEUTIC CATEGORYVET THERAPEUTIC CATEGORY
potent inhibitor of neuronal nitric oxide synthase
reduces the lesion volume after transient the middle cerebral artery occlusion in rats
REFERENCE
Handy RL, et al. The antinociceptive effect of 1-(2-trifluoromethylphenyl) imidazole (TRIM), a potent inhibitor of neuronal nitric oxide synthase in vitro, in the mouse. Br J Pharmacol. 1995 Nov;116(5):2349-50
Escott KJ, et al. Cerebroprotective effect of the nitric oxide synthase inhibitors, 1-(2-trifluoromethylphenyl) imidazole and 7-nitro indazole, after transient focal cerebral ischemia in the rat. J Cereb Blood Flow Metab. 1998 Mar;18(3):281-7

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3'-Adenylic acid ST013860 ST013860 $61.00

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3'-Adenylic acid ST013860

MFCD01456450

C10H14N5O7P

347.22


IDENTIFIER
IDNUMBERNAMECASMDL
ST0138603'-Adenylic acid84-21-9MFCD01456450
IUPACNAME
2-(6-aminopurin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl dihydrogen phosph ate
Smiles
C(C1OC(n2c3c(c(N)ncn3)nc2)C(C1O)OP(=O)(O)O)O
Chem-Physical
FormulaMolecular WeightSALT
C10H14N5O7P347.22
LogPLogSLipinskyAcceptors
-4.65-1.5337
DonorsRotation BondsChiral CentersN+O
68412
SOURCE
from yeast
REFERENCE
Merk 13, 158
Merk 13, 6759

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all-trans-Retinoic acid; Tretinoin; vitamin A acid ST057075 ST057075 $61.00

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all-trans-Retinoic acid; Tretinoin; vitamin A acid ST057075

302794

MFCD00001551

C20H28O2

300.44


IDENTIFIER
IDNUMBERNAMECASMDL
ST057075all-trans-Retinoic acid; Tretinoin; vitamin A acid302-79-4MFCD00001551
IUPACNAME
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetr aenoic acid
Smiles
C1(/C=CC(=C/C=CC(=C/C(=O)O)C)C)=C(CCCC1(C)C)C
Chem-Physical
FormulaMolecular WeightSALT
C20H28O2300.44
LogPLogSLipinskyAcceptors
7.31-5.5632
DonorsRotation BondsChiral CentersN+O
1602
SOURCE
Physiological metabolite of vitamin A
REFERENCE
Merk 13, 8251
Bollag W, Ott F. Vitamin A acid in benign and malignant epithelial tumours of the skin. Acta Derm Venereol Suppl (Stockh). 1975 Jan 27-29;74:163-6
Zancai P, et al. Retinoic acid inhibits IL-6-dependent but not constitutive STAT3 activation in Epstein-Barr virus-immortalized B lymphocytes. Int J Oncol. 2004 Aug;25(2):345-55

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Amorphigenin ST024783 ST024783 $61.00

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Amorphigenin ST024783

MFCD02184614

C23H22O7

410.42


IDENTIFIER
IDNUMBERNAMECASMDL
ST024783Amorphigenin843231MFCD02184614
IUPACNAME
2-(2-hydroxy-1-methyleneethyl)-8,9-dimethoxy-1,2-dihydrochromano[3,4-b]furano[ 2,3-h]chroman-6-one
Smiles
c1(cc2c(cc1OC)OCC1C2C(c2c(O1)c1c(cc2)OC(C1)C(CO)=C)=O)OC
Chem-Physical
FormulaMolecular WeightSALT
C23H22O7410.42
LogPLogSLipinskyAcceptors
3.23-4.747
DonorsRotation BondsChiral CentersN+O
1537
SOURCE
Root bark of Berchemia discolor; Amorpha fruticosa
REFERENCE
Chin YW, et al. Prenylated flavonoids from the root bark of Berchemia discolor, a Tanzanian medicinal plant. J Nat Prod. 2006 Nov;69(11):1649-52
Li L, et al. Antitumor agents, 138. Rotenoids and isoflavones as cytotoxic constitutents from Amorpha fruticosa. J Nat Prod. 1993 May;56(5):690-8

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Apigenin ST056301 ST056301 $61.00

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Apigenin ST056301

520-36-5

MFCD00006831

C15H10O5

270.24


IDENTIFIER
IDNUMBERNAMECASMDL
ST056301Apigenin520-36-5MFCD00006831
IUPACNAME
5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Smiles
c12c(cc(oc1cc(cc2O)O)c1ccc(cc1)O)=O
Chem-Physical
FormulaMolecular WeightSALT
C15H10O5270.24
LogPLogSLipinskyAcceptors
1.24-3.1745
DonorsRotation BondsChiral CentersN+O
3305
SOURCE
The aglycon of linarin; Flowers of Clerodendron infortunatum
REFERENCE
Merk 13, 13
Sinha NK, et al. Flavonoids from the Flowers of Clerodendron infortunatum. Planta Med. 1981 Jul;42(7):296-8
Amellal M, et al. Inhibition of mast cell histamine release by flavonoids and biflavonoids. Planta Med. 1985 Feb;51(1):16-20
Kellis JT Jr, Vickery LE. Inhibition of human estrogen synthetase (aromatase) by flavones. Science. 1984 Sep 7;225(4666):1032-4

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Bemesetron; MDL 72222 ST046674 ST046674 $61.00

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Bemesetron; MDL 72222 ST046674

MFCD00078562

C15H17Cl2NO2

314.21


IDENTIFIER
IDNUMBERNAMECASMDL
ST046674Bemesetron; MDL 72222MFCD00078562
IUPACNAME
8-methyl-8-azabicyclo[3.2.1]oct-3-yl 3,5-dichlorobenzoate
Smiles
CN1C2CC(CC1CC2)OC(c1cc(Cl)cc(c1)Cl)=O
Trademark
Chem-Physical
FormulaMolecular WeightSALT
C15H17Cl2NO2314.21
LogPLogSLipinskyAcceptors
4.87-4.7942
DonorsRotation BondsChiral CentersN+O
0223
ACTIVITY
THERAPEUTIC CATEGORYVET THERAPEUTIC CATEGORY
Selective blocking actions at certain excitatory 5-hydroxytryptamine (5-HT) receptors on mammalian peripheral neurones
REFERENCE
Fozard JR. MDL 72222: a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors. Naunyn Schmiedebergs Arch Pharmacol. 1984 May;326(1):36-44

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Bracteoline ST057703 ST057703 $61.00

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Bracteoline ST057703

MFCD07189860

C19H21NO4

327.38


IDENTIFIER
IDNUMBERNAMECASMDL
ST057703Bracteoline25651-04-1MFCD07189860
IUPACNAME
Smiles
c12c3c(c(cc1CCN([C@H]2(Cc1c3cc(c(c1)OC)O))C)OC)O
Trademark
Chem-Physical
FormulaMolecular WeightSALT
C19H21NO4327.38
LogPLogSLipinskyAcceptors
3.55-4.3344
DonorsRotation BondsChiral CentersN+O
2415
ACTIVITY
THERAPEUTIC CATEGORYVET THERAPEUTIC CATEGORY
Inhibits mouse splenocyte activity
REFERENCE
Denisenko, O.N., et al. Alkaloids of Papaver bracteatum. Chemistry of Natural Compounds. Volume 13, Number 4 / July, 1978, 456-458
Philipov S, et al. Glaucine analogues as inhibitors of mouse splenocyte activity. Pharmazie. 1998 Oct;53(10):694-8

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Brefeldin A, natural ST056354 ST056354 $61.00

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Brefeldin A, natural ST056354

20350-15-6

MFCD05618218

C16H24O4

280.36


IDENTIFIER
IDNUMBERNAMECASMDL
ST056354Brefeldin A, natural20350-15-6MFCD05618218
IUPACNAME
(7S,15S,1R)-2,15-dihydroxy-7-methyl-6-oxabicyclo[11.3.0]hexadeca-3,11-dien-5-o ne
Smiles
C1[C@H](CC2[C@@H]1[C@@H](C=CC(=O)O[C@H](CCCC=C2)C)O)O
Trademark
Chem-Physical
FormulaMolecular WeightSALT
C16H24O4280.36
LogPLogSLipinskyAcceptors
3.15-4.1244
DonorsRotation BondsChiral CentersN+O
2054
ACTIVITY
THERAPEUTIC CATEGORYVET THERAPEUTIC CATEGORY
Antibiotic
A fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity
Antiviral
blocks intracellular transport of secretory proteins (from the endoplasmic reticulum to the Golgi complex) in cultured rat hepatocytes
REFERENCE
Merk 13, 1355
Misumi Y, et al. Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes. J Biol Chem. 1986 Aug 25;261(24):11398-403
Tsai SC, et al. Effects of brefeldin A and accessory proteins on association of ADP-ribosylation factors 1, 3, and 5 with Golgi. J Biol Chem. 1993 May 25;268(15):10820-5

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