NHS-dPEG®4-(m-dPEG®x)3-ester

Amount: 100mg

Item Name: NHS-dPEG®4-(m-dPEG®4)3-ester

Item #: 10411

Mol. Wt.: 1363.54;

single compound dPEG® Spacer is 43 atoms and 46.2 A

Product Features and Benefits: Amine reactive, activated ester, a dPEG® based tribranched pegylation reagent. Each is a single compound; made synthetically from 99.5% pure tetraethylene glycol. Imparts incredible water solubility, and the pegylation reagent itself is non-immunogenic and non-toxic, passing these properties to the modified agent. Potentially very useful as a drug/protein modifier to specifically increase hydrodynamic volume. Produces compounds with reduced aggregation, or surfaces with reduced non-specific binding in diagnostic applications Produces very stable amide bond

Reference: Greg T. Hermanson, Bioconjugate Techniques, 2nd Ed, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0)., See pp. 276-335 for general description and use of heterobifunctional crosslinkers, and the specific sample protocol for SMCC or sulfo-SMCC on pp. 283-286.

Amount: 100mg

Item Name: NHS-dPEG®4-(m-dPEG®24)3-ester

Item #: 10454

Mol. Wt.; 4006.69;

single compound dPEG® Spacer is 103 atoms and 107.1 A approx.

Product Features and Benefits: Amine reactive, activated ester, a dPEG® based tribranched pegylation reagent. Each is a single compound; made synthetically from 99.5% pure tetraethylene glycol. Imparts incredible water solubility, and the pegylation reagent itself is non-immunogenic and non-toxic, passing these properties to the modified agent. Potentially very useful as a drug/protein modifier to specifically increase hydrodynamic volume. Produces compounds with reduced aggregation, or surfaces with reduced non-specific binding in diagnostic applications Produces very stable amide bond

Reference: Greg T. Hermanson, Bioconjugate Techniques, 2nd Ed, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0)., See pp. 276-335 for general description and use of heterobifunctional crosslinkers, and the specific sample protocol for SMCC or sulfo-SMCC on pp. 283-286.